Onconova Therapeutics, Inc.
375 Pheasant Run
Newtown, PA 18954
May 15, 2020
Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
|Celeste M. Murphy|
|Re:||Onconova Therapeutics, Inc.|
|Registration Statement on Form S-3|
|Filed April 24, 2020|
|File No. 333-237844|
Ladies and Gentlemen:
Pursuant to Rule 461 under the Securities Act of 1933, as amended, Onconova Therapeutics, Inc. (the “Company”) hereby requests acceleration of the effective date of the above referenced registration statement, as amended, so that such registration statement may become effective at 4:30 p.m. (Washington, D.C. time) on May 18, 2020, or as soon as practicable thereafter.
|ONCONOVA THERAPEUTICS, INC.|
|By:||/s/ MARK GUERIN|
|Title:||Chief Financial Officer|